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Dimension EXL with LM Integrated Chemistry System

Overview                   
 
System Description Random-access clinical chemistry and immunoassay system with LOCI®  chemiluminescence technology
Test Throughput Performs up to 440 photometric chemistry tests per hour and 187 IMT tests per hour on serum, plasma, urine, and cerebrospinal fluid; can perform up to 167 heterogeneous immunoassay tests per hour
Time to First Result IMT (NA, K, CL): 1.5 min; Electrolytes (IMT + ECO2): 2.9 min; BMP-7  Electrolytes, GLU, BUN, CREA) 4.0 min; CMP-6 (ALB, DBIL, TBIL, AST, ALT, ALP): 9.3 min; TNI: 11 min; HCG: 15.5 min
Assay Capacity Onboard 91 including 3 IMT
Disease-state Assay
Groups
Anemia, Autoimmune/Rheumatoid, Bone Metabolism, Cardiovascular, Diabetes, Drugs of Abuse/Toxicology, Hepatic Diseases, Immunosuppressive Drugs/TDM, Inflammation, Nephropathies, Nutritional Assessment, Pancreatic Disease, Oncology, Reproductive Endocrinology, Thyroid
   
Sample Handling  
Sample Tubes 5 mL, 7 mL, 10 mL tubes; 1.5 mL sample cups; 1.0 mL small sample containers and pediatric tubes
Sample Wheel 60 sample positions in six 10-tube segments; positive sample identification
STAT Handling Not dedicated; STAT samples are processed with priority
Sample Integrity
Check
Qualitative check for hemolysis, lipemia, and icterus; clot detection, flagging, and management; short-sample detection, flagging, and management
Auto-Repeat Automatic repeat testing from the original sample
Sample Volume Per Test 2–60 μL
Sample Dilution Automatic dilution: 1:1.5 up to 1:200
Auto-Reflex Testing Automatic reflex testing based on results of first test
Primary Sample Probe Liquid-level sensing, clot detection, short-sample detection
Sample Carryover Prevention Automated wash
Sample Throughput Up to 200 tubes per hour as part of the VersaCell® X3 Solution – Dimension® Suite; faster on automation
   
Bar Codes  
Sample Bar Codes Code 39; Code 128; Codabar (USS); Interleaved 2 of 5 w and w/o check digit, 12 digits maximum
   
Reaction Area  
Reaction Cuvettes Onboard capacity of 12,000 formed cuvettes
Reaction Bath Air; incubation temperature 37°C
Path Length 0.5 cm ±0.0125 cm
Photometer The filter wheel holds optical filters for wavelengths of 293, 340, 383, 405, 452, 510, 540, 577, 600, 680, and 700 nm
Light Source Standard tungsten halogen lamp, operation at 6.5A (6.8v)
Reaction Times 1, 3, 4, 5, 10, 15, 21, and 32 minutes
Automatic Correction Serum blank, cell blank, reagent blank, measurement point change, autodilution
Assay Technologies LOCI, heterogeneous immunoassay, PETINIA and ACMIA, photometry, potentiometry (ISE), turbidimetric, and Emit®
Assay Result Calculations Endpoint, rate, multipoint
   
Reagent Handling  
Reagent Tray 2 trays, 44 positions, refrigerated between 2–8°C (36–47°F); one on the Reagent Management System (RMS)
Reagent Capacity Onboard 88 Flex® Reagent Cartridges plus 3 electrolytes via the QuikLYTE® IMT
Dispensing System 3 probes with liquid-level sensing
Reagent Cartridges Flex Reagent Cartridges, bar coded, 15 to 360 tests/Flex
Average Total
Reaction Volume
350–500 μL per test
Reagent
Integrity Control
Bar-code reagent identification; automatic inventory tracking and flagging; calibration and control validity tracking and flagging; reagent onboard tracking of tests remaining, lot number, onboard stability, and expiration date
Onboard Stability Depending on assay, up to 42 days
Test Capacity
Onboard
25,200 tests average; 33,300 tests maximum
   
Open System Capability
 
Channels 110 assay channels; includes 10 channels for user-defined applications
   
IMT  
IMT Indirect simultaneous measurement of Na+, K+, Cl-
Sample Volume 40 μL for all three tests
Priming Automatic priming cycle, no user calibration, automatic urine dilution 1:10
Expected Use 1000 samples or 5 days, whichever comes first
   
Calibration/QC  
Validated Calibration
Interval
Up to 90 days, tracked by software, with 500 most recent calibration logs stored electronically if a system restore is required (starting with software version 10.1)
Auto-Calibration Assay-specific time interval or with new reagent lot
Auto-QC User-defined time interval
View Calibration Graphical display of calibration curves
QC Data Graphical display of QC plot (histogram or Levey-Jennings) with Westgard Rules; RealTime QC; QCC PowerPak™ efficiency package
   
User Interface/Data Management  
Monitor 17-inch diagonal touchscreen with adjustable height
Operating Computer Linux, 1 GB RAM
System Documentation Operator manual
Data Storage 100,000 patient tests (10 MB), 100,000 QC results (10 MB), 9000 calibrations (5 yrs, 18 MB)
Auto-System Check User-defined time of day
Host Interface RS 232C bidirectional
Host Query System requests work order or batch of work orders from host
Remote Access
and Service
Ethernet port for remote access via Siemens Remote Service (starting with software version 10.1); modem
for remote diagnostic access
   
Removable Media  
Removable Media CD, DVD, and USB (starting with software version 10.0)
   
General Specifications  
Power Requirements
System
115 VAC at 60 Hz (nominal); 11 amps max; 1.3 kW consumption in operating state 230 VAC at 50 Hz (nominal); 5.5 amps max; 1.3 kW consumption in operating state
Power Requirements RMS 115 VAC at 60 Hz (nominal); 4 amps max; 450 W consumption in operating state 230 VAC at 50 Hz (nominal); 3 amps max; 450 W consumption in operating state
Water Specifications1
  • Instrument feed pressurized water source
  • <3.8 bar (<55 psi)
  • Instrument feed water system must maintain
  • stable DO2 content between 5 and 8 ppm²
  • Temperature: <35°C (<95°F)
  • Resistivity: >10 megohms cm
  • Bacterial content: <10 colony forming units/mL
  • System feed water line must not exceed 3 m (12 feet)
Water System
  • Instrument may be supplied with a water purifier that provides instrument feed water
  • If an alternative water system is used, water must adhere to Siemens water specifications
Maximum Water
Consumption
5.0 L/hr (1.32 gal/hr)
Drain Requirements 40 L/hr (10.6 gal/hr)
Dimensions Normal operation: 252 cm W x 122 cm H x 132 cm D (99 in. W x 48 in. H x 52 in. D) With monitor fully extended, lids fully open, and external UPS: 255 cm W x 191 cm H x 155 cm D (100 in. W x 75 in. H x 61 in. D)
Weight 496 kg (1095 lb)
Compliance Complies with international environmental, health, and safety standards
Noise Specifications <75 dBA at 1 m while operating
Average Heat Output 1551 W/hr (5293 BTU/hr)
Operating Temperature Range 18–30ºC (64–86ºF)
Ambient Humidity 20–80% (noncondensing)

 

References:
1. Meets the definition of CLSI Clinical Laboratory Reagent Water (Clinical Laboratory Standards Institute, C3-A4, Vol. 26, No. 22).
2. Not applicable to CLSI Clinical Laboratory Reagent Water (CLRW), but required for proper instrument performance.

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