Siemens Eclipse™ cyclotron, an 11 MeV negative ion single particle accelerator, produces Curie levels of positron emitting radioisotopes — 18F, 11C, 13N and 15O. Its self-shielded, automated design offers you fast, easy and efficient production of PET radioisotopes. Higher energy cyclotrons produce more neutrons of higher energy, which in turn, increase activation of surrounding vault walls. This activation is minimized with the 11 MeV Eclipse. Using advanced technology, Eclipse targetry offers efficient production of PET isotopes with minimal use of enriched starting materials such as 18O water. Our systems offer high-yields with reliable uptime. When it comes to the production of radiotracers, we see the ability to be automated yet flexible as key to producing consistent high yields. So we have simplified the production process and this in turn reduces the workload on your staff.
Eclipse’s unique sector design, with a valley-to-hill gap ratio of 27:1, enables high-quality beam focusing. This means improved beam transmission, greater production yields and greatly reduced internal activation. Eclipse uses a patented single-coil magnet that dramatically reduces the system’s power consumption. High efficiency supports high production capabilities along with low operating costs.
Eclipse targets are designed to enable easy installation and removal, minimizing radiation exposure to service personnel. Changing targets does not require breaking the accelerator vacuum, contributing to the system's excellent uptime. There are two target carousel formats available on Eclipse – Eclipse HP and Eclipse RD. Eclipse HP target carousel holds up to four high-volume targets per beam line capable of running at up to 60 µA. Eclipse RD target carousel holds up to eight low volume targets per beam line capable of running at up to 40 µA. Both systems support production of 18F [F-], 18F [F2], 15O [O2], 13N Ammonia and 11C [CO2], but Eclipse RD cannot be outfitted with solid targets for production of 64Cu Copper or 18F [F-] target bodies made of tantalum. Optional dual extraction further allows two target changers to be mounted and the capability to simultaneously produce two different isotopes or to double the quantity of a single isotope.
Eclipse’s self-shielded system substantially reduces radiation levels without the expense and space required for a vault. The dose at room boundary (7.62 m × 7.62 m × 4.57 m height; 25 ft × 25 ft × 15 ft height) is <2.0 mR/hour. The Eclipse self-shield is an engineered containment system, including a negative pressure effluent containment, prompt radiation shielding and interlocked access control. This eliminates the cost of vault design for the facility. The system is also available without the self-shield for installation in existing vault spaces. The design of Eclipse cyclotron reduces decommissioning costs as well since the self-shield can easily be removed without demolition at decommissioning, further reducing total cost of ownership.
All major systems on Eclipse are automatically controlled through a Windows® workstation. The control software incorporates an easy-to-use interface. The Eclipse control system also allows you to initiate production remotely and within minutes the system is ready to irradiate a target. You can easily control all functions of the cyclotron, which allows you to optimize performance.
Vertical mounting of the ion source and extraction mechanism provides easy access and reduced maintenance time. The extraction carousel’s multiple, long-lived stripping foils enable extended operation before service is required.